KEGG   REACTION: R04419
Entry
R04419                      Reaction                               
Name
5-carboxymethyl-2-hydroxymuconic-semialdehyde:NADP+ oxidoreductase
Definition
2-Hydroxy-5-carboxymethylmuconate semialdehyde + NADP+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00254  C04186_C04642
Enzyme
Pathway
rn00350  Tyrosine metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.312
     R04419  2-Hydroxy-5-carboxymethylmuconate semialdehyde + NADP+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH + H+
Orthology
K10219  2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]

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